An Overview on Herbal Medicine used in the Treatment of Alzheimer’s Disease
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Date
2022-05Author
Yadav, Anuj
Dr. Prem Shankar Mishra, (Supervisor)
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Impacts, anticholinesterase impacts, hypolipidemic impacts and cancer prevention agent
influences. Researchers have been looking at a variety of medicinal plants that have showed
promise in reversing the pathology of Alzheimer's disease, and they have gathered their
findings here. Pharmacological targets and treatment concepts that are often used are
discussed below. As a result, natural compounds operating in a phototherapeutic manner are
shown to have advantages over AD monotherapy. This method emphasises the use of many
Alzheimer's disease (AD) is characterised by severe memory loss, which may have a
significant impact on one's social and professional lives. More than 20 million individuals
throughout the globe suffer from this kind of dementia, making it the most prevalent.
Alzheimer's disease (AD) is characterised by a gradual loss of memory, as well as a reduction
in cognitive and behavioural abilities. A decade or more after being diagnosed with AD,
patients may still be living, making it the most common cause of impairment among the
elderly. AD may affect anywhere from 1% to 4% of the population each year, with rates
peaking around age 65-70 and dropping to as low as 6% for those over 85. Acetylcholine was
the first neurotransmitter to be shown to be defective in Alzheimer's disease (A Ch). At this
time, there is no known cure for Alzheimer's disease, and present medications only have
limited efficacy in treating the condition. Delaying or halting the course of Alzheimer's
disease might significantly lower the number of instances in people over the next 50 years,
according to experts. One of the most fruitful sources of drug development leads has been
Ayurvedic medicinal herbs, and over one hundred novel medications are now in clinical
development. The utilization of Ayurvedic restorative plants and their elements for the
treatment of Alzheimer's illness has been shown by a few logical examinations. Despite the
fact that the specific system by which they work is as yet a secret, phytochemical
investigations of different plant parts have shown the presence of numerous important
mixtures, for example, lignans, flavonoids, tannins, polyphenols, triterpenes, steroids and
alkaloids that show a wide range of pharmacological exercises, including calming impacts,
against amyloidogenic mechanisms, such as antioxidant and anti-inflammatory general
processes and receptor and/or enzyme-mediated actions, in the search for new drugs to
protect and regenerate the brain.
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